News and Announcements

A new story of the road:

Two new preprints:

New paper published:

P.J. Cunningham, P.S. Regier, A.D. Redish (in press) “Dorsolateral striatal task-initiation bursts represent past experiences more than future action plansJournal of Neuroscience.

New paper published:

A. A. Duin, L. Aman, B. Schmidt, A. D. Redish (2021) “Certainty and uncertainty of the future changes planning and sunk costsBehavioral Neuroscience. https://doi.org/10.1037/bne0000460

New paper published:

L. T. Hunt, N. D. Daw, P. Kaanders, M. A. MacIver, U. Mugan, E. Procyk, A. D. Redish, E. Russo, J. Scholl, K. Stachenfeld, C. R. E. Wilson, N. Kolling (2021) “Formalising planning and information search in naturalistic decision-makingNature Neuroscience. https://doi.org/10.1038/s41593-021-00866-w

Two new papers published!

O. L. Calvin, A. D. Redish (2021) “Global Disruption in Excitation-Inhibition Balance Can Cause Localized Network Dysfunction and Schizophrenia-Like Context-Integration DeficitsPLoS Computational Biology 17(5): e1008985.

B. Schmidt, A. D. Redish (2021) “Disrupting the medial prefrontal cortex with DREADDs alters hippocampal sharp-wave ripples and their associated cognitive processesHippocampus. 10.1002/hipo.23367. 1-17.


Congratulations to now-lab-alum now-Dr. Cody Walters, PhD.  Cody is off to join the editorial staff at Cell.


See the new UMN Legacy article on what we're doing at NeuroPRSMH:

Meeting of the minds:Through creative collaboration, U of M neuroscientists and mental health experts are translating scientific breakthroughs into life-changing care.https://legacy.umn.edu/stories/meeting-of-the-minds


New paper published

R. Kazinka, A. W. MacDonald III, A. D. Redish (2021) “Sensitivity to sunk costs depends on attention to the delayFrontiers in Psychology 12:373.


New paper available

A.E. McLaughlin, G.W. Diehl, A.D. Redish (in press) Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems. International Review of Neurobiology.


New chapter out as part of a new book edited by Peggy Series. 

A. D. Redish (2020) “Addiction from a Computational Perspective” in Computational Psychiatry: A Primer, P. Series (ed) Chapter 9, pgs. 185-204 MIT Press.


New paper published

B. M. Hasz, A. D. Redish (2020) Spatial encoding in dorsomedial prefrontal cortex and hippocampus is related during deliberation. Hippocampus 30:1194-1208.


New paper in press!

C.S.J. Chen, R.B. Ebitz, S. Bindas, A.D. Redish, B. Hayden, N.M. Grissom (in press) Divergent strategies for learning in males and females. Current Biology


New paper now available.

B. M. Hasz, A. D. Redish (in press) Spatial encoding in dorsomedial prefrontal cortex and hippocampus is related during deliberation. Hippocampus.


Final version now available.

E. Kummerfeld, S. Ma, R. K. Blackman, A. L. DeNicola, A. D. Redish, S. Vinogradov, D. A. Crowe, M. V. Chafee (2020) Cognitive control errors in nonhuman primates resembling those in schizophrenia reflect opposing effects of NMDAR blockade on causal interactions between cells and circuits in prefrontal and parietal cortex.     Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 5(7):705-714.


Final version now available.

B. M. Hasz, A. D. Redish (2020) Dorsomedial prefrontal cortex and hippocampus represent strategic context even while simultaneously changing representation throughout a task session. Neurobiology of Learning and Memory 171:107215.


Congratulations to lab alum Dr. (soon to be Dr.Dr.) Brian Sweis, who matched to the physician-scientist track at the Icahn School of Medicine at Mount Sinai NYC!


Two new papers in press!

  • E. Kummerfeld, S. Ma, R. K. Blackman, A. L. DeNicola, A. D. Redish, S. Vinogradov, D. A. Crowe, M. V. Chafee (in press) Cognitive control errors in nonhuman primates resembling those in schizophrenia reflect opposing effects of NMDAR blockade on causal interactions between cells and circuits in prefrontal and parietal cortex.     Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
  • B. M. Hasz, A. D. Redish (in press) Dorsomedial prefrontal cortex and hippocampus represent strategic context even while simultaneously changing representation throughout a task session. Neurobiology of Learning and Memory.

Announcing our translational psychiatry workgroup, called NeuroPRSMH (Neuroscience Plasticity Research in Support of Mental Health), bringing together faculty collaborating on questions of neuropasticity, computational psychiatry, and the neuroscience of innovative treatment approaches for psychiatric illness.  The new website (neuroprsmh.umn.edu) is now live!   And we are now funded by a new P50 (MH119569)!


The talk ADR gave at the IPAM / UCLA Computational Psychiatry Workshop (full schedule with talks here) is now available online: Cross-species translation through computational analyses - implications for understanding and modifying psychiatric treatments.


Congratulations to newly minted Lab PhD (now Dr.) Brendan Hasz who defended his thesis Model-free and Model-based Influence on Choice in Rodents and Interactions between Hippocampus and Prefrontal Cortex during Deliberation on Friday 10 Jan 2020!


New paper published!

S. V. Abram, M. Hanke, A. D. Redish, A. W. MacDonald (2019) Neural signatures underlying deliberation in human foraging decisions. Cognitive, Affective, & Behavioral Neuroscience, 19(6):1492-1508. .


Congratulations to lab member/alumnus Brian Sweis, who won the Donald B. Lindsley prize for the "outstanding PhD thesis in the area of general behavioral neuroscience" from SFN this year!


Come see our posters at SFN 2019

  • 335.01. Disrupting medial prefrontal cortex with DREADDs alters hippocampal place cell firing in sharp wave ripples in rats (Brandy Schmidt) [Monday 21/Oct: BB24]

  • 335.02. Representation of choice and value in the ventral striatum during the restaurant row task (Geoff Diehl, w/ Brandy Schmidt and Yannick Breton) [Monday 21/Oct: BB25]

  • 335.03. Goal encoding in prelimbic cortex and CA1 on a contingency-switching task for rats (Brendan Hasz) [Monday 21/Oct: BB26]

  • 335.04. Human cocaine users, like cocaine-treated mice, display unique disruptions on a neuroeconomic task (Brian Sweis, w/ Jazmin Camchong, Sam Abram, Sheila Specker, Angus MacDonald, Mark Thomas, and Kelvin Lim) [Monday 21/Oct: BB27]

  • 335.05. Neuroeconomic decision-making in J20 mice (Rachel Anderson, w/ Brian Sweis, Damyan Hart, Matthew Sherman, Sylvain Lesne, and Mark Thomas). [Monday 21/Oct: BB28]

  • Predictive uncertainty changes rat behavior on foraging tasks (Anneke Duin and London Aman, w/ Brandy Schmidt).  At the Faculty for Undergraduate Neuroscience Poster Session on Sunday evening (SOC04  in Room N226)


MClust

  • The MClust spike sorting toolboox is now available as a publicly accessible repository on github.com.  Version 4.4.07 has been uploaded to start.